Pharmacy School Researchers May Find Options for Untreatable Diseases

Pharmacy schools and medical colleges throughout the world are notorious for being the birthplaces of revolutionary new ways to look at medicine.

Research-based learning hospitals and college programs have led to everything from cures to preventions in some of our most concerning ailments.

The pharmacy school at the University of North Carolina is on such a path with a treatment for Angelman Syndrome, according a UNC news publication. Angelman Syndrome is a disorder of the nervous system with no cure and no proven treatment options.

Commonly, Angelman Syndrome causes speech impairment by disallowing signals to pass through the system, literally robbing a person of their voice causing difficulty with or inability to speak. The researchers at the pharmacy school have identified a protein that can be produced in brain cells that allow the signals for speech to pass through the system.

In cases of Angelman Syndrome, the gene that produces this protein lies dormant. But the pharmacy school may have stumbled on a way to activate it, essentially waking this part of the system up and calling it to duty. In cooperation with scientists at the pharmacy school, the researchers may have opened the pathway to treating the disease.

The pharmacy school research used a variety of drugs to find a way to wake the gene responsible for creating the necessary protein. All of their research was conducted on laboratory mice, which seemed to respond to a medication known as “irinotecan”.

While the researchers readily admit that they are nowhere near to a viable, user friendly treatment they are hopeful for a future treatment for this disease.

“We’d like to stress that these compounds are not ready to be used clinically for Angelman syndrome,” said Mark J. Zylka, a neuroscientist and professor at the pharmacy college. “We need to figure out optimal concentrations and dosing before we move to clinical trials. And we need to determine which drug is best.”

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  1. SocialSave says:

    Pharmacy School Researchers May Find Options for Untreatable Diseases…

    Pharmacy schools and medical colleges throughout the world are notorious for being the birthplaces of revolutionary new ways to look at medicine….

  2. pligg.com says:

    Pharmacy School Researchers May Find Options for Untreatable Diseases…

    Pharmacy schools and medical colleges throughout the world are notorious for being the birthplaces of revolutionary new ways to look at medicine….